Litcius/Paper detail

Discovery of YK-029A, a novel mutant EGFR inhibitor targeting both T790 M and exon 20 insertion mutations, as a treatment for NSCLC

Bin Liu, Feng Gao, Huijun Zhao, Shuai Yuan, Xingzhe Peng, Pengzhi Zhang, Jing Wang, Tongmei Zhang, Maosheng Duan, Yongqi Guo

2023European Journal of Medicinal Chemistry17 citationsDOIOpen Access PDF

Topics & Concepts

ExonEpidermal growth factor receptorMutantCancer researchEGFR inhibitorsMutationChemistryIn vivoPharmacologyCancerBiologyGeneGeneticsBiochemistryLung Cancer Treatments and MutationsCancer therapeutics and mechanismsColorectal Cancer Treatments and Studies