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Neuroepithelial VIP–VIPR1 interactions differentially control enteric type 1 and type 2 immunity

Roksana M. Pirzgalska, Beatriz Henriques-Alves, Bruno Raposo, Eric de Sousa, Júlio Torres, Jaechan Ryu, Cristina Godinho‐Silva, Miguel Rendas, M E Pereira, Inês Godinho, Hélder Ribeiro, Vasco Correia, Manuel O. Jakob, Patrycja M. Forster, Christoph Wilhelm, Christoph S. N. Klose, Ricardo Rio‐Tinto, Verena M. Link, Tânia Carvalho, Carlos M. Minutti, Manuela Ferreira, Henrique Veiga‐Fernandes

2025Nature Immunology12 citationsDOI

Topics & Concepts

Neuroepithelial cellBiologyIntraepithelial lymphocyteCell biologyImmunityEnteric nervous systemImmune systemInnate immune systemImmunologyCell typeReceptorVasoactive intestinal peptideEpitheliumIntestinal epitheliumInnate lymphoid cellCentral nervous systemIntestinal mucosaAcquired immune systemCytokineEnterochromaffin cellGut floraT cellWild typeCellGastrointestinal motility and disordersCongenital gastrointestinal and neural anomaliesBarrier Structure and Function Studies
Neuroepithelial VIP–VIPR1 interactions differentially control enteric type 1 and type 2 immunity | Litcius