Viral recombination systems limit CRISPR-Cas targeting through the generation of escape mutations
Amer A. Hossain, Jon McGinn, Alexander J. Meeske, Joshua W. Modell, Luciano A. Marraffini
Topics & Concepts
CRISPRBiologyRecBCDGeneticsRecombinationBacteriophageHomologous recombinationCas9GenomeDNAGenome editingFLP-FRT recombinationGeneComputational biologyGenetic recombinationEscherichia coliCRISPR and Genetic EngineeringEvolution and Genetic DynamicsInsect symbiosis and bacterial influences