Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity
Erping Long, Jinhu Yin, Karen Funderburk, Mai Xu, James Feng, Alexander Kane, Tongwu Zhang, Timothy A. Myers, Alyxandra Golden, Rohit Thakur, Hyunkyung Kong, Lea Jessop, Eun Young Kim, Kristine Jones, Raj Chari, Mitchell J. Machiela, Kai Yu, Mark M. Iles, Maria Teresa Landi, Matthew H. Law, Stephen J. Chanock, Kevin M. Brown, Jiyeon Choi
Topics & Concepts
BiologyExpression quantitative trait lociGenome-wide association studyGeneticsLocus (genetics)GeneQuantitative trait locusComputational biologyGenomeEpigenomicsSingle-nucleotide polymorphismGenotypeDNA methylationGene expressionGenomics and Chromatin DynamicsGenetic Associations and EpidemiologyBioinformatics and Genomic Networks