Litcius/Paper detail

Host Immunity Alters Community Ecology and Stability of the Microbiome in a Caenorhabditis elegans Model

Megan Taylor, Nic M. Vega

2021mSystems40 citationsDOIOpen Access PDF

Abstract

microbiome model to demonstrate how genetic differences in innate immunity alter microbiome composition, diversity, and stability by changing the ecological processes that shape these communities. These results provide insight into the role of host genetics in controlling the ecology of the host-associated microbiota, resulting in differences in community composition, successional trajectories, and response to perturbation.

Topics & Concepts

MicrobiomeBiologyCaenorhabditis elegansEcologyInnate immune systemHost (biology)ImmunityEvolutionary biologyModel organismCommunityImmune systemGeneticsGeneEcosystemGut microbiota and healthGenetics, Aging, and Longevity in Model OrganismsTryptophan and brain disorders