Host Immunity Alters Community Ecology and Stability of the Microbiome in a Caenorhabditis elegans Model
Megan Taylor, Nic M. Vega
Abstract
microbiome model to demonstrate how genetic differences in innate immunity alter microbiome composition, diversity, and stability by changing the ecological processes that shape these communities. These results provide insight into the role of host genetics in controlling the ecology of the host-associated microbiota, resulting in differences in community composition, successional trajectories, and response to perturbation.
Topics & Concepts
MicrobiomeBiologyCaenorhabditis elegansEcologyInnate immune systemHost (biology)ImmunityEvolutionary biologyModel organismCommunityImmune systemGeneticsGeneEcosystemGut microbiota and healthGenetics, Aging, and Longevity in Model OrganismsTryptophan and brain disorders