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Ionic Liquids and Ohmic Heating in Combination for Pd-Catalyzed Cross-Coupling Reactions: Sustainable Synthesis of Flavonoids

Vera L. M. Silva, Raquel G. Soengas, Artur M. S. Silva

2020Molecules16 citationsDOIOpen Access PDF

Abstract

In order to meet the increasing demand for environmentally benign chemical processes, we developed a Suzuki-Miyaura reaction protocol based on the combination of ohmic heating (ΩH) and supported ionic liquid phase catalysis (SILPC) in aqueous media. This methodology was applied to the synthesis of a series of flavonoid derivatives, including isoflavones, styrylisoflavones, and diarylalkenylisoflavones.

Topics & Concepts

Ionic liquidCatalysisChemistryIsoflavonesIonic bondingJoule heatingGreen chemistryAqueous mediumOhmic contactCoupling reactionCombinatorial chemistryOrganic chemistryAqueous solutionMaterials scienceBiochemistryIonComposite materialLayer (electronics)Catalytic Cross-Coupling ReactionsMulticomponent Synthesis of HeterocyclesCatalytic C–H Functionalization Methods
Ionic Liquids and Ohmic Heating in Combination for Pd-Catalyzed Cross-Coupling Reactions: Sustainable Synthesis of Flavonoids | Litcius