Phloretin and phloridzin guard against cisplatin-induced nephrotoxicity in mice through inhibiting oxidative stress and inflammation
Harun Ün, Rüstem Anıl Uğan, Muhammet Ali Gürbüz, Yasin Bayır, Aysenur Kahramanlar, Gökçe Kaya, Elif Çadırcı, Zekai Halıcı
Topics & Concepts
NephrotoxicityOxidative stressChemistryPharmacologyGlutathioneCreatininePhloretinCisplatinInflammationAntioxidantToxicityKidneyRenal functionBiochemistryEndocrinologyInternal medicineEnzymeMedicineChemotherapyOrganic chemistryChemotherapy-induced organ toxicity mitigationChemotherapy-induced cardiotoxicity and mitigationCircadian rhythm and melatonin