Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43
Yi Xiao Jiang, Qin Cao, M.R. Sawaya, Romany Abskharon, P. Ge, Michael DeTure, Dennis W. Dickson, Janine Y. Fu, Rachel R. Ogorzalek Loo, Joseph A. Loo, David Eisenberg
Topics & Concepts
Frontotemporal lobar degenerationFibrilChemistryTransmembrane proteinImmunogold labellingAmyloid (mycology)Cerebral amyloid angiopathyPathologyBiophysicsBiologyBiochemistryFrontotemporal dementiaMedicineDementiaUltrastructureDiseaseReceptorParkinson's Disease Mechanisms and TreatmentsAmyotrophic Lateral Sclerosis ResearchNeurological diseases and metabolism