The protective effects of dulaglutide against advanced glycation end products (AGEs)-induced degradation of type Ⅱ collagen and aggrecan in human SW1353 chondrocytes
Hai Li, Jianhai Chen, Biao Li, Xiaoyan Fang
Topics & Concepts
ADAMTSDulaglutideAggrecanGlycationType II collagenProinflammatory cytokineThrombospondinChemistryExtracellular matrixMatrix metalloproteinaseOsteoarthritisArthritisDownregulation and upregulationEndocrinologyInternal medicineCell biologyInflammationReceptorMedicineMetalloproteinaseBiochemistryBiologyType 2 diabetesExenatidePathologyDiabetes mellitusGeneArticular cartilageAlternative medicineAdvanced Glycation End Products researchInflammatory mediators and NSAID effectsOsteoarthritis Treatment and Mechanisms