The ellagitannin metabolite urolithin C attenuated cognitive impairment by inhibiting neuroinflammation via downregulation of MAPK/NF-kB signaling pathways in aging mice
Peng Chen, Lining Wu, Jiexin Lei, Fuchao Chen, Lihua Feng, Gang Liu, Benhong Zhou
Topics & Concepts
EllagitanninDownregulation and upregulationMAPK/ERK pathwayMetaboliteNeuroinflammationChemistrySignal transductionPharmacologyMedicineInflammationBiochemistryAntioxidantImmunologyPolyphenolGenePomegranate: compositions and health benefitsAntioxidant Activity and Oxidative StressBioactive Compounds in Plants