Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy
Jianying Qi, Yuanyuan Wu, Zhimou Guo, Shenglong Zhu, Jingjing Xiong, Fei Hu, Xinmiao Liang, Xianlong Ye
Topics & Concepts
PI3K/AKT/mTOR pathwayIdiopathic pulmonary fibrosisAutophagyPulmonary fibrosisProtein kinase BCancer researchBleomycinFibroblastFibrosisEpithelial–mesenchymal transitionChemistrySignal transductionMedicineLungCell biologyPathologyBiologyInternal medicineApoptosisDownregulation and upregulationBiochemistryChemotherapyGeneIn vitroFibroblast Growth Factor ResearchInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis