Litcius/Paper detail

RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in colorectal cancer cells

Jing Wang, Jia Wang, Ling Li, Li Feng, Yurong Wang, Zhe Wang, Ning‐Hua Tan

2020Journal of Ethnopharmacology32 citationsDOI

Topics & Concepts

AutophagyPI3K/AKT/mTOR pathwayApoptosisProtein kinase BCell cycle checkpointClonogenic assayCell cycleBiologyCancer researchBiochemistryQuinazolinone synthesis and applicationsPharmacological Effects of Natural CompoundsMorinda citrifolia extract uses