Schizandrol A protects against Aβ1–42-induced autophagy via activation of PI3K/AKT/mTOR pathway in SH-SY5Y cells and primary hippocampal neurons
Lin Song, Lifen Yao, Limei Zhang, Zhongyuan Piao, Yichan Lu
Topics & Concepts
PI3K/AKT/mTOR pathwayAutophagyProtein kinase BSH-SY5YCell biologyChemistryApoptosisLY294002Programmed cell deathOxidative stressBiologyBiochemistryCell cultureNeuroblastomaGeneticsAlzheimer's disease research and treatmentsPlant-derived Lignans Synthesis and BioactivityAutophagy in Disease and Therapy