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Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial

Aditya Bardia, Wells A. Messersmith, Ebenezer A. Kio, Jordan Berlin, Linda T. Vahdat, Gregory A. Masters, R Moroose, Alessandro D. Santin, Kevin Kalinsky, Vincent J. Picozzi, Joyce O’Shaughnessy, Jhanelle E. Gray, Takefumi Komiya, Joshua M. Lang, Jenny C. Chang, Alexander Starodub, David M. Goldenberg, Robert M. Sharkey, Pius Maliakal, Q. Hong, William A. Wegener, Trishna Goswami, Allyson J. Ocean

2021Annals of Oncology377 citationsDOI

Topics & Concepts

MedicineInternal medicineTolerabilityNeutropeniaPopulationGastroenterologyPhases of clinical researchAdverse effectAntibody-drug conjugateOncologyClinical trialSurgeryChemotherapyImmunologyAntibodyEnvironmental healthMonoclonal antibodyHER2/EGFR in Cancer ResearchAdvanced Breast Cancer TherapiesCancer Cells and Metastasis
Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial | Litcius