Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial
Aditya Bardia, Wells A. Messersmith, Ebenezer A. Kio, Jordan Berlin, Linda T. Vahdat, Gregory A. Masters, R Moroose, Alessandro D. Santin, Kevin Kalinsky, Vincent J. Picozzi, Joyce O’Shaughnessy, Jhanelle E. Gray, Takefumi Komiya, Joshua M. Lang, Jenny C. Chang, Alexander Starodub, David M. Goldenberg, Robert M. Sharkey, Pius Maliakal, Q. Hong, William A. Wegener, Trishna Goswami, Allyson J. Ocean
Topics & Concepts
MedicineInternal medicineTolerabilityNeutropeniaPopulationGastroenterologyPhases of clinical researchAdverse effectAntibody-drug conjugateOncologyClinical trialSurgeryChemotherapyImmunologyAntibodyEnvironmental healthMonoclonal antibodyHER2/EGFR in Cancer ResearchAdvanced Breast Cancer TherapiesCancer Cells and Metastasis