Factors Associated with Mortality among Hospitalized Patients with COVID-19: A Retrospective Cohort Study
Paulo Ricardo Martins‐Filho, Adriano Antunes de Souza Araújo, Luciana Xavier Pereira, Lucindo José Quintans‐Júnior, Waneska de Souza Barboza, Taíse Ferreira Cavalcante, Mércia Feitosa de Souza, Marco Aurélio de Oliveira Góes, Victor Santana Santos
Abstract
Information on the risk factors for COVID-19 mortality in low- and middle-income countries is still scarce. In this retrospective cohort study, we analyzed the factors associated with COVID-19 mortality in hospitalized patients in a poor area of Brazil. Logistic regression was used to identify factors independently associated with mortality, including gender, age, and the presence of underlying medical conditions. A total of 1,207 patients were included in the analysis, and a 1.5-fold increase in COVID-19 mortality was found among patients aged > 65 years with hypertension and diabetes (odds ratio [OR]: 1.50, 95% CI: 1.02-2.19). Moreover, infectious disease (OR: 4.31, 95% CI: 1.39-13.39), kidney disease (OR: 2.59, 95% CI: 1.27-5.27), and heart disease (OR: 2.00, 95% CI: 1.31-3.04) were also predictive for COVID-19 in-hospital death. This large cohort provides important data on potential factors associated with COVID-19 mortality in Brazil.