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Long-term potentiation: 50 years on: past, present and future

W. C. Abraham, Tim Bliss, Graham L. Collingridge, Richard Morris

2024Philosophical Transactions of the Royal Society B Biological Sciences13 citationsDOIOpen Access PDF

Abstract

We introduce and summarize reviews and research papers by speakers at a discussion meeting on 'Long-term potentiation: 50 years on' held at the Royal Society, London, on 20-21 November 2023. The meeting followed earlier discussion meetings marking the 30th and 40th anniversaries of the discovery of long-term potentiation. These new contributions give an overview of current research and controversies in a vibrant branch of neuroscience with important implications for our understanding of the neurobiological basis of many forms of learning and memory and a wide spectrum of neurological and cognitive disorders.This article is part of a discussion meeting issue 'Long-term potentiation: 50 years on'.

Topics & Concepts

Long-term potentiationTerm (time)NeurosciencePsychologyCognitive scienceMedicineInternal medicineReceptorPhysicsQuantum mechanicsNeuroscience and Neuropharmacology ResearchIon channel regulation and functionMemory and Neural Mechanisms
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