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The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development

Tianpeng Gu, Dapeng Hao, Junsung Woo, Teng-Wei Huang, Lei Guo, Xueqiu Lin, Anna Guzman, Ayala Tovy, Carina Rosas, Mira Jeong, Yubin Zhou, Benjamin Deneen, Yun Huang, Wei Li, Margaret A. Goodell

2022Nature Genetics88 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTerminal (telecommunication)Domain (mathematical analysis)Cell biologyComputational biologyGeneticsComputer scienceComputer networkMathematicsMathematical analysisEpigenetics and DNA MethylationRenal and related cancersCancer-related gene regulation
The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development | Litcius