Target Volume Definition for Stereotactic Radiosurgery (SRS) Of Cerebral Cavernous Malformations (CCMS)
Omer Sager
Abstract
Objective: Cerebral cavernous malformations (CCMs) are composed of abnormal hyalinized capillary clusters typically surrounded by deposits of hemosiderin. These vascular abnormalities of the brain may be asymptomatic, however, a plethora of symptoms may occur in some of the affected patients including seizures, hemorrhages, and neurological deficits. Stereotactic radiosurgery (SRS) has been utilized as a noninvasive modality of management for selected patients with high risk CCMs located at eloquent brain regions typically not amenable to surgical removal. In this study, we assessed incorporation of multimodality imaging into target volume definition of CCM radiosurgery.
Topics & Concepts
RadiosurgeryMedicineAsymptomaticCavernous malformationsHemosiderinRadiologySusceptibility weighted imagingMagnetic resonance imagingNuclear medicinePathologyRadiation therapyVascular Malformations Diagnosis and TreatmentIntracranial Aneurysms: Treatment and ComplicationsGlioma Diagnosis and Treatment