Small rings in the bigger picture: ring expansion of three- and four-membered rings to access larger all-carbon cyclic systems
Bohdan Biletskyi, P Colonna, Kévin Masson, Jean‐Luc Parrain, Laurent Comméiras, Gaëlle Chouraqui
Abstract
The release of the inherent ring strain of cyclobutane and cyclopropane derivatives allows a rapid build-up of molecular complexity. This review highlights the state-of-the-art of the ring expansions of three- and four-membered cycles and is organised by types of reactions with emphasis on the reaction mechanisms. Selected examples are discussed to illustrate the synthetic potential of this elegant synthetic tool.
Topics & Concepts
Ring (chemistry)Ring sizeCarbon fibersAromaticityCrystallographyMaterials scienceChemistryMoleculeComposite materialOrganic chemistryComposite numberSynthetic Organic Chemistry MethodsCyclopropane Reaction MechanismsCatalytic Alkyne Reactions