Free docosahexaenoic acid promotes ferroptotic cell death via lipoxygenase dependent and independent pathways in cancer cells
Kai Shan, Ninghan Feng, Doudou Zhu, Hongyan Qu, Guoling Fu, Jiaqi Li, Jing Cui, Heyan Chen, Rong Wang, Yumin Qi, Yong Q. Chen
Topics & Concepts
Docosahexaenoic acidLipoxygenaseProgrammed cell deathCancer cellCancerArachidonate 5-lipoxygenaseChemistryCancer researchCell biologyCellApoptosisBiologyBiochemistryEnzymeArachidonic acidFatty acidPolyunsaturated fatty acidGeneticsFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCancer, Stress, Anesthesia, and Immune Response