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Near UV and Visible Light Photo-Degradation Mechanisms in Citrate Buffer: One-Electron Reduction of Peptide and Protein Disulfides promotes Oxidation and Cis/Trans Isomerization of Unsaturated Fatty Acids of Polysorbate 80

Indira Prajapati, Natalia Subelzú, Yilue Zhang, Yaqi Wu, Christian Schöneich

2022Journal of Pharmaceutical Sciences28 citationsDOI

Topics & Concepts

ChemistryIsomerizationPhotochemistryRadicalRedoxReducing agentElectron transferOrganic chemistryCatalysisProtein purification and stabilityProtein Hydrolysis and Bioactive PeptidesViral Infectious Diseases and Gene Expression in Insects
Near UV and Visible Light Photo-Degradation Mechanisms in Citrate Buffer: One-Electron Reduction of Peptide and Protein Disulfides promotes Oxidation and Cis/Trans Isomerization of Unsaturated Fatty Acids of Polysorbate 80 | Litcius