Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
Nandini Acharya, Asaf Madi, Huiyuan Zhang, Max Klapholz, Giulia Escobar, Shai Dulberg, Elena Christian, Michelle Ferreira, Karen O. Dixon, Geoffrey Fell, Katherine Tooley, Davide Mangani, Junrong Xia, Meromit Singer, Marcus Bosenberg, Donna Neuberg, Orit Rozenblatt–Rosen, Aviv Regev, Vijay K. Kuchroo, Ana C. Anderson
Topics & Concepts
Tumor microenvironmentBiologyCancer researchCytotoxic T cellCD8T cellSignal transductionCell biologyGlucocorticoidCancer immunotherapyImmunotherapyImmunologyImmune systemBiochemistryIn vitroTumor cellsImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses