n → π* interactions as a versatile tool for controlling dynamic imine chemistry in both organic and aqueous media
Hang Chen, Hebo Ye, Haitao Yu, Ling Zhang, Lei You
Abstract
-carboxylate containing aldehydes were used to regulate imine formation/exchange in water, and modification of the N-terminus of amino acids and peptides was achieved in a neutral buffer. This work represents the latest example of weak interactions governing DCC and sets the stage for assembly and application studies.
Topics & Concepts
ImineChemistryAqueous mediumAqueous solutionCombinatorial chemistryOrganic chemistryComputational chemistryCatalysisCrystallography and molecular interactionsSupramolecular Chemistry and ComplexesMolecular Sensors and Ion Detection