Understanding the effects of ethanol on the liposome bilayer structure using microfluidic-based time-resolved small-angle X-ray scattering and molecular dynamics simulations
Masatoshi Maeki, Niko Kimura, Yuto Okada, Kazuki Shimizu, Kana Shibata, Yusuke Miyazaki, Akihiko Ishida, Kento Yonezawa, Nobutaka Shimizu, Wataru Shinoda, Manabu Tokeshi
Abstract
We investigated ethanol-induced structural changes in liposomes on a time scale from microseconds to tens of seconds using a microfluidic-based small-angle X-ray scattering (SAXS) measurement system coupled with molecular dynamics (MD) simulations.
Topics & Concepts
Small-angle X-ray scatteringMolecular dynamicsMicrofluidicsScatteringLiposomeMicrosecondBilayerMaterials scienceChemical physicsDynamics (music)NanotechnologyCrystallographyMembraneChemistryOpticsComputational chemistryPhysicsAcousticsBiochemistryNanopore and Nanochannel Transport StudiesCharacterization and Applications of Magnetic NanoparticlesForce Microscopy Techniques and Applications