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Cytokine Stimulation by MRGPRX2 Occurs with Lower Potency than by FcεRI Aggregation but with Similar Dependence on the Extracellular Signal–Regulated Kinase 1/2 Module in Human Skin Mast Cells

Zhao Wang, Kristin Franke, Torsten Zuberbier, Magda Babina

2021Journal of Investigative Dermatology20 citationsDOI

Topics & Concepts

KinaseExtracellularp38 mitogen-activated protein kinasesCell biologySignal transductionBiologyCytokinePhosphorylationMast cellMAPK/ERK pathwayImmunologyMast cells and histamineUrticaria and Related ConditionsAsthma and respiratory diseases
Cytokine Stimulation by MRGPRX2 Occurs with Lower Potency than by FcεRI Aggregation but with Similar Dependence on the Extracellular Signal–Regulated Kinase 1/2 Module in Human Skin Mast Cells | Litcius