A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
Guy Zoltsman, Thi Lieu Dang, Miriam Kuchersky, Ofrah Faust, Micael Silva, Tal Ilani, Anne S. Wentink, Bernd Bukau, Rina Rosenzweig
Topics & Concepts
BiologyChaperone (clinical)Co-chaperoneMutantCell biologyProtein foldingMechanism (biology)Computational biologyHsp70Heat shock proteinBiochemistryGenePhilosophyMedicineEpistemologyPathologyHeat shock proteins researchProtein Structure and DynamicsEnzyme Structure and Function