A p21-ATD mouse model for monitoring and eliminating senescent cells and its application in liver regeneration post injury
Miaomiao Chen, Guoxiu Wu, Yanli Lu, Shiwen Sun, Yu Zhao, Xin Pan, Wenjian Chen, Jin Xu, Hua Qiu, Weizhi He, Xiuhua Li, Xicheng Wang, Yi Luo, Yuan Du, Jialing Wu, Ke Wei, Wencheng Zhang, Zhongmin Liu, Zhiying He
Topics & Concepts
SenescenceBiologyCell biologyRegeneration (biology)Diphtheria toxinCell sortingIn vivoCellFlow cytometryGenetically modified mouseIn vitroTransgeneImmunologyGeneGeneticsToxinTelomeres, Telomerase, and SenescenceRNA Interference and Gene DeliveryMicroRNA in disease regulation