Di-(2-ethylhexyl) phthalate exposure induces premature testicular senescence by disrupting mitochondrial respiratory chain through STAT5B-mitoSTAT3 in Leydig cell
Haiming Cao, Qigen Xie, Peng Luo, Jiaqi Chen, Kai Xia, Lin Ma, Demeng Chen, Chunhua Deng, Zi Wan
Topics & Concepts
PhthalateEndocrinologyTestosterone (patch)Internal medicineSenescenceLeydig cellBiologyMitochondrionMitochondrial respiratory chainIn vivoReproductive toxicityTesticleSteroidogenic acute regulatory proteinAndrologyToxicityChemistryHormoneMedicineGene expressionBiochemistryGeneLuteinizing hormoneGeneticsOrganic chemistryEffects and risks of endocrine disrupting chemicalsPluripotent Stem Cells ResearchTelomeres, Telomerase, and Senescence