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EasyNanopore: A Ready-to-Use Processing Software for Translocation Events in Nanopore Translocation Experiments

Jing Tu, Hao Meng, Linlin Wu, Guohao Xi, Jiye Fu, Zuhong Lu

2021Langmuir15 citationsDOI

Abstract

We developed EasyNanopore which is a ready-to-use software to select the events of a nanopore molecular translocation experiment. The software is released as an executable file with a graphical user interface and provides several versions suitable for different operating systems without installing any running environment to execute it. We use the adaptive threshold which adapts to the low-frequency variation of the baseline to detect events and uses a multiprocess method to accelerate the process of event detection. After the event is identified, its duration and amplitude information will be extracted and a resulting txt file will be generated for further analysis. Our software runs fast and can effectively extract the data from data of large-scale nanopore molecular translocation experiments.

Topics & Concepts

NanoporeComputer scienceSoftwareExecutableEvent (particle physics)Chromosomal translocationInstallationOperating systemChemistryNanotechnologyMaterials sciencePhysicsBiochemistryGeneQuantum mechanicsNanopore and Nanochannel Transport StudiesGeophysical and Geoelectrical MethodsIon-surface interactions and analysis
EasyNanopore: A Ready-to-Use Processing Software for Translocation Events in Nanopore Translocation Experiments | Litcius