Litcius/Paper detail

Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk

Joshua Chiou, Chun Zeng, Cheng Zhang, Jee Yun Han, Michael Schlichting, Michael Miller, Robert Mendez, Serina Huang, Jinzhao Wang, Yinghui Sui, Allison Deogaygay, Mei-Lin Okino, Yunjiang Qiu, Ying Sun, Parul Kudtarkar, Rongxin Fang, Sebastian Preißl, Maike Sander, David U. Gorkin, Kyle J. Gaulton

2021Nature Genetics191 citationsDOIOpen Access PDF

Topics & Concepts

BiologyChromatinEnhancerEpigenomicsCell typeTranscription factorGeneticsBeta cellIsletComputational biologyCellGeneInsulinGene expressionEndocrinologyDNA methylationPancreatic function and diabetesSingle-cell and spatial transcriptomicsError Correcting Code Techniques