Are Zn(<scp>ii</scp>) pincer complexes efficient apoptosis inducers? a deep insight into their activity against A549 lung cancer cells
Athulya Das, Muniyandi Sankaralingam
Abstract
DCFDA staining. Interestingly, the present complexes show better activity than that of the standard drug cisplatin against A549 cells. Overall, the studies provided promising results that can be extended for clinical applications.
Topics & Concepts
ApoptosisA549 cellFlow cytometryCisplatinChemistryPincer movementMTT assayCytotoxicityCell cultureMolecular biologyCancer cellStainingLigand (biochemistry)IC50Cancer researchCancerBiologyBiochemistryIn vitroReceptorChemotherapyGeneticsCatalysisMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activity