Molecular and Clinical Characterization of Multidrug-Resistant and Hypervirulent Klebsiella pneumoniae Strains from Liver Abscess in Taiwan
Yi-Tsung Lin, Yi-Hsiang Cheng, Chien Chuang, Sheng-Hua Chou, Wan-Hsin Liu, Chi-Han Huang, Tsuey‐Ching Yang, Barry N. Kreiswirth, Liang Chen
Abstract
Hypervirulent Klebsiella pneumoniae strains are the major cause of liver abscesses throughout East Asia, and these strains are usually antibiotic susceptible. Recently, multidrug-resistant and hypervirulent (MDR-HV) K. pneumoniae strains have emerged due to hypervirulent strains acquiring antimicrobial resistance determinants or the transfer of a virulence plasmid into a classic MDR strain. In this study, we characterized the clinical and microbiological properties of K. pneumoniae liver abscess (KPLA) caused by MDR-HV strains in Taiwan.
Topics & Concepts
Klebsiella pneumoniaeMicrobiologyMultiple drug resistanceLiver abscessVirulenceBiologyAntibioticsAntibiotic resistancePlasmidKlebsiellaVirologyAbscessGeneEscherichia coliGeneticsAntibiotic Resistance in BacteriaAmoebic Infections and TreatmentsSalmonella and Campylobacter epidemiology