The phytase RipBL1 enables the assignment of a specific inositol phosphate isomer as a structural component of human kidney stones
Guizhen Liu, Esther Riemer, Robin Schneider, Daniela Cabuzu, Olivier Bonny, Carsten A. Wagner, Danye Qiu, Adolfo Saiardi, Annett Strauß, Thomas Lahaye, Gabriel Schaaf, Thomas Knoll, Jan Peter Jessen, Henning J. Jessen
Abstract
Kidney stones and patient urine contain inositol 1,2,3-trisphosphate as demonstrated by capillary electrophoresis mass spectrometry with an internal heavy isotope reference.
Topics & Concepts
ChemistryCapillary electrophoresisPhosphateMass spectrometryEnantiomerElectrospray ionizationChromatographyBiochemistryStereochemistryPhytase and its ApplicationsTrace Elements in HealthFolate and B Vitamins Research