DNA Origami Design: A How-To Tutorial
Jacob M. Majikes, J. Alexander Liddle
2021Journal of Research of the National Institute of Standards and Technology22 citationsDOIOpen Access PDF
Abstract
While the design and assembly of DNA origami are straightforward, its relative novelty as a nanofabrication technique means that the tools and methods for designing new structures have not been codified as well as they have for more mature technologies, such as integrated circuits. While design approaches cannot be truly formalized until design-property relationships are fully understood, this document attempts to provide a step-by-step guide to designing DNA origami nanostructures using the tools available at the current state of the art.
Topics & Concepts
DNA origamiNoveltyComputer scienceProperty (philosophy)NanotechnologyNanolithographyDesign elements and principlesSystems engineeringSoftware engineeringEngineering drawingNanostructureEngineeringMaterials sciencePathologyMedicineTheologyEpistemologyPhilosophyAlternative medicineFabricationAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionRNA Interference and Gene Delivery