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Levulinic Acid Hydrogenation with Homogeneous Cu(I) Catalyst

Tamara Jurado‐Vázquez, Efrén Rosaldo, Alma Arévalo, Juventino J. Garcı́a

2022ChemCatChem12 citationsDOIOpen Access PDF

Abstract

Abstract We report the first well‐defined homogeneous copper‐based catalyst for levulinic acid (LVA) hydrogenation using complex [(PPh 3 ) 2 Cu(k 2 ‐O,O‐LVA)] as a copper source and (1,2‐bis(diisopropyl phosphino)ethane (dippe) as an ancillary ligand. This catalytic precursor has high activity in LVA hydrogenation and yields γ‐valerolactone (GVL) under relatively mild reaction conditions (24 h, 140 °C) in a base‐free system using H 2 (300 psi) as a reductant. Under optimized conditions, GVL was obtained with excellent yield (>99 %) and selectivity (>99 %) using a low catalytic load (0.025 mol %), allowing a TON=4000.

Topics & Concepts

Levulinic acidCatalysisHomogeneousHomogeneous catalysisChemistrySelectivityCopperYield (engineering)Ligand (biochemistry)Base (topology)Organic chemistryMedicinal chemistryNuclear chemistryMaterials scienceMetallurgyMathematicsReceptorBiochemistryMathematical analysisPhysicsThermodynamicsCatalysis for Biomass ConversionAsymmetric Hydrogenation and CatalysisCatalysis and Hydrodesulfurization Studies
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