EGCG-crosslinked carboxymethyl chitosan-based hydrogels with inherent desired functions for full-thickness skin wound healing
Qingcong Wei, Lin Ma, Weiwei Zhang, Guanglei Ma, Zhiguo Hu
Abstract
. In the subsequent full-thickness skin defect model of mice, EP1 gel could promote the proliferation and remodeling process such as the regeneration of epidermis, dermis, and skin appendages, deposition of collagen, and upregulation of the VEGF level, thereby accelerating the healing of damaged skin. Overall, we facilely prepared polysaccharide-based hydrogels with inherent desirable properties as promising dressings for wound repair.
Topics & Concepts
Self-healing hydrogelsChitosanWound healingMaterials scienceWound dressingBiomedical engineeringSelf-healingChemical engineeringPolymer chemistryComposite materialSurgeryMedicineEngineeringPathologyAlternative medicineWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsPeriodontal Regeneration and Treatments