Rucaparib antagonize multidrug resistance in cervical cancer cells through blocking the function of ABC transporters
Zhen Chen, Kaijian Ling, Yingjun Zhu, Li Deng, Yudi Li, Zhiqing Liang
Topics & Concepts
ATP-binding cassette transporterMultiple drug resistanceBiologyPharmacologyEffluxCancer researchAbcg2Drug resistancePaclitaxelCancer cellCancerTransporterBiochemistryMicrobiologyGeneticsGeneDrug Transport and Resistance MechanismsCancer therapeutics and mechanismsPARP inhibition in cancer therapy