Are microplastics contributing to pollution-induced neurotoxicity? A pilot study with wild fish in a real scenario
Luís Gabriel A. Barboza, Xosé Luís Otero, Ezequiel V. Fernández, Luís R. Vieira, José O. Fernandes, Sara C. Cunha, Lúcia Guilhermino
Abstract
Pollution-induced neurotoxicity is of high concern. This pilot study investigated the potential relationship between the presence of microplastics (MPs) in the brain of 180 wild fish ( Dicentrarchus labrax , Platichthys flesus, Mugil cephalus ) from a contaminated estuary and the activity of the acetylcholinesterase (AChE) enzyme. MPs were found in 9 samples (5% of the total), all of them from D. labrax collected in the summer, which represents 45% of the samples of this species collected in that season (20). Seventeen MPs were recovered from brain samples, with sizes ranging from 8 to 96 μm. Polyacrylamide, polyacrylic acid and one biopolymer (zein) were identified by Micro-Raman spectroscopy. Fish with MPs showed lower (p ≤ 0.05) AChE activity than those where MPs were not found. These findings point to the contribution of MPs to the neurotoxicity induced by long-term exposure to pollution, stressing the need of further studies on the topic to increase ‘One Health' protection.