Supramolecular catalysis by recognition-encoded oligomers: discovery of a synthetic imine polymerase
Luca Gabrielli, Christopher A. Hunter
Abstract
trimer was found to catalyse oligomerisation the phosphine oxide dialdehyde with the diamine linker, suggesting an important role for the backbone in catalysis. This unexpected imine polymerase activity in a duplex-forming synthetic oligomer suggests that there are many interesting processes to be discovered in the chemistry of synthetic recognition-encoded oligomers that will parallel those found in natural biopolymers.
Topics & Concepts
ImineSupramolecular chemistryCatalysisCombinatorial chemistryPolymeraseChemistryEnzymeSynthetic biologyComputational biologyStereochemistryBiochemistryBiologyOrganic chemistryMoleculeChemical Synthesis and AnalysisSupramolecular Chemistry and ComplexesSupramolecular Self-Assembly in Materials