Non-Equilibrium Thermodynamic Foundations of the Origin of Life
Karo Michaelian
Abstract
There is little doubt that life’s origin followed from the known physical and chemical laws of Nature. The most general scientific framework incorporating the laws of Nature and applicable to most known processes to good approximation, is that of thermodynamics and its extensions to treat out-of-equilibrium phenomena. The event of the origin of life should therefore also be amenable to such an analysis. In this review paper, I describe the non-equilibrium thermodynamic foundations of the origin of life for the non-expert from the perspective of the “Thermodynamic Dissipation Theory for the Origin of Life” which is founded on Classical Irreversible Thermodynamic theory developed by Lars Onsager, Ilya Prigogine, and coworkers. A Glossary of Thermodynamic Terms can be found at the end of the article to aid the reader.