Metal–Organic Framework Nanomaterials as a Medicine for Catalytic Tumor Therapy: Recent Advances
Jiaojiao Zhang, Jiaojiao Zhang, Meiyu Li, Maosong Liu, Qian Yu, Dengfeng Ge, Jianming Zhang, Jianming Zhang
Abstract
Nanomaterials, with unique physical, chemical, and biocompatible properties, have attracted significant attention as an emerging active platform in cancer diagnosis and treatment. Amongst them, metal-organic framework (MOF) nanostructures are particularly promising as a nanomedicine due to their exceptional surface functionalities, adsorption properties, and organo-inorganic hybrid characteristics. Furthermore, when bioactive substances are integrated into the structure of MOFs, these materials can be used as anti-tumor agents with superior performance compared to traditional nanomaterials. In this review, we highlight the most recent advances in MOFs-based materials for tumor therapy, including their application in cancer treatment and the underlying mechanisms.