The pattern of apolipoprotein A-I lysine carbamylation reflects its lipidation state and the chemical environment within human atherosclerotic aorta
Shawna Battle, Valentin Gogonea, Belinda Willard, Zeneng Wang, Xiaoming Fu, Ying Huang, Linda M. Graham, Scott J. Cameron, Joseph A. DiDonato, John W. Crabb, Stanley L. Hazen
Abstract
pathway. Monitoring patterns of apoA-I carbamylation recovered from arterial tissues can provide insights into both apoA-I structure and the chemical environment within human atheroma.
Topics & Concepts
Lipid-anchored proteinLysineAortaApolipoprotein BBiochemistryChemistryInternal medicineCholesterolMedicineAutophagyAmino acidApoptosisDiabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic DiseasesAdvanced Glycation End Products research