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A double-network strategy for the tough tissue adhesion of hydrogels with long-term stability under physiological environment

Shuyang Wang, Jieru Li, Yudong Pan, Fengkai Liu, Liangsong Zeng, Yang Gao, Tongqing Lu

2022Soft Matter18 citationsDOI

Abstract

with porcine tissues, and the maximal adhesion could be maintained for over 1000 min after submerging in a PBS solution at 37 °C. The swelling behavior of the hydrogel and changes in mechanical properties under the physiological environment are studied, and its application in repairing the aorta wound is demonstrated.

Topics & Concepts

Self-healing hydrogelsAdhesionCovalent bondSwellingAdhesiveMaterials scienceTissue AdhesionNanotechnologyBiomedical engineeringChemistryPolymer chemistryComposite materialLayer (electronics)Organic chemistryMedicineHydrogels: synthesis, properties, applicationsSurgical Sutures and AdhesivesPolymer Surface Interaction Studies