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The Functional Roles of <i>Lactobacillus acidophilus</i> in Different Physiological and Pathological Processes

Huijuan Gao, Xin Li, Xiatian Chen, Hai Deng, Chuang Wei, Lei Zhang, Peifeng Li

2022Journal of Microbiology and Biotechnology158 citationsDOIOpen Access PDF

Abstract

Probiotics are live microorganisms that can be consumed by humans in amounts sufficient to offer health-promoting effects. Owing to their various biological functions, probiotics are widely used in biological engineering, industry and agriculture, food safety, and the life and health fields. Lactobacillus acidophilus (L. acidophilus), an important human intestinal probiotic, was originally isolated from the human gastrointestinal tract and its functions have been widely studied ever since it was named in 1900. L. acidophilus has been found to play important roles in many aspects of human health. Due to its good resistance against acid and bile salts, it has broad application prospects in functional, edible probiotic preparations. In this review, we explore the basic characteristics and biological functions of L. acidophilus based on the research progress made thus far worldwide. Various problems to be solved regarding the applications of probiotic products and their future development are also discussed.

Topics & Concepts

Lactobacillus acidophilusProbioticHuman healthBiotechnologyBiologyFunctional foodHealth benefitsHuman gastrointestinal tractGastrointestinal tractMicrobiologyFood scienceMedicineBiochemistryBacteriaTraditional medicineEnvironmental healthGeneticsProbiotics and Fermented FoodsMicrobial Metabolites in Food BiotechnologyGut microbiota and health