Raloxifene-loaded SLNs with enhanced biopharmaceutical potential: QbD-steered development, in vitro evaluation, in vivo pharmacokinetics, and IVIVC
Atul Jain, Teenu Sharma, Rajendra Kumar, Om Prakash Katare, Bhupinder Singh
Topics & Concepts
ChemistryIVIVCIn vivoPharmacologyZeta potentialLactate dehydrogenasePharmacokineticsBioavailabilityBiopharmaceuticalCytotoxicityChromatographyMTT assayIn vitroDissolution testingMaterials scienceBiochemistryNanotechnologyMedicineBiopharmaceutics Classification SystemNanoparticleBiotechnologyGeneticsBiologyEnzymeEstrogen and related hormone effectsAnalytical Chemistry and ChromatographyDrug Solubulity and Delivery Systems