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Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials

Florian Wagenlehner, Caroline Perry, Thomas M. Hooton, Nicole E. Scangarella-Oman, Helen Millns, Marcy Powell, Emily Jarvis, Jeremy Dennison, Amanda Sheets, Deborah Butler, John Breton, Salim Janmohamed

2024The Lancet82 citationsDOI

Topics & Concepts

NitrofurantoinEagleMedicineUrinary systemDouble blindInternal medicineGastroenterologySurgeryPlaceboAntibioticsCiprofloxacinPathologyBiologyMicrobiologyAlternative medicinePaleontologyCancer therapeutics and mechanismsUrinary Tract Infections ManagementAntibiotics Pharmacokinetics and Efficacy
Oral gepotidacin versus nitrofurantoin in patients with uncomplicated urinary tract infection (EAGLE-2 and EAGLE-3): two randomised, controlled, double-blind, double-dummy, phase 3, non-inferiority trials | Litcius