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Advances in asymmetric organocatalysis over the last 10 years

Shao‐Hua Xiang, Bin Tan

2020Nature Communications272 citationsDOIOpen Access PDF

Abstract

Beyond esoteric interest, organocatalysis has now become one major pillar of asymmetric catalysis. Here, we discuss how new activation modes are conquering challenging stereoselective transformations and the recent integration of organocatalysis with emerging photo- and electrocatalysis, as well as artificial intelligence. Organocatalysis has become a major pillar of (asymmetric) catalysis. Here, the authors discuss recent trends in organocatalytic activation modes for challenging stereoselective transformations and the emerging integration with other fields, such as photoredox catalysis and electrosynthesis.

Topics & Concepts

OrganocatalysisEnantioselective synthesisPillarElectrocatalystChemistryNanotechnologyCatalysisMaterials scienceOrganic chemistryEngineeringStructural engineeringElectrochemistryPhysical chemistryElectrodeRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsAsymmetric Synthesis and Catalysis