Dinuclear osmium complexes as mitochondrion-targeting antitumor photothermal agents<i>in vivo</i>
Mengfan Wang, Yu‐Ang Deng, Qingfang Li, Shi‐Jie Tang, Rong Yang, Runyu Zhao, Fu-Dan Liu, Xiaoxia Ren, Dan Zhang, Feng Gao
Abstract
Mitochondrion-targeting dinuclear osmium complexes with extremely high photothermal conversion capability under irradiation of an 808 nm low-power laser without nucleus affinity and photodynamic activity act as antitumor photothermal therapy agents in vivo .
Topics & Concepts
Photothermal therapyIn vivoOsmiumMitochondrionChemistryBiophysicsIrradiationPhotodynamic therapyNanotechnologyCombinatorial chemistryBiochemistryMaterials scienceBiologyRutheniumOrganic chemistryBiotechnologyNuclear physicsCatalysisPhysicsNanoplatforms for cancer theranosticsMetal complexes synthesis and propertiesClick Chemistry and Applications