Accuracy of Nasal Pressure Swing to Predict Failure of High-Flow Nasal Oxygen in Patients with Acute Hypoxemic Respiratory Failure
Roberto Tonelli, Andrea Cortegiani, Riccardo Fantini, Luca Tabbì, Ivana Castaniere, Giulia Bruzzi, Stefano Busani, Lorenzo Ball, Enrico Clini, Alessandro Marchioni
Abstract
In a real-life cohort of patients with AHRF undergoing HFNO, ΔPnose showed excellent accuracy in predicting early failure, similar of that displayed by ROX. Giving that the decision to upgrade to NIV or MV was based on clinical variables, the high accuracy of ROX in predicting failure of HFNO is not surprising. The similar accuracy of ΔPnose (the only measurement that remained blinded to our clinical decision), strengthened the association with outcome, avoiding incorporation bias.
Topics & Concepts
MedicineRespiratory failureAcute respiratory failureIntensive care medicineAnesthesiaMechanical ventilationRespiratory Support and MechanismsAirway Management and Intubation TechniquesNeonatal Respiratory Health Research