Multicomponent Dehydrogenative Synthesis of Acridine‐1,8‐diones Catalyzed by Ru‐doped Hydrotalcite
Bitan Sardar, Ramen Jamatia, Debjyoti Pal, Dipankar Srimani
Abstract
Abstract The usage of biomass‐derived chemicals to synthesize pharmaceutically important heterocyclic scaffold via acceptorless dehydrogenation is an emerging trend in chemistry. Herein, we describe the applicability of Ru‐doped hydrotalcite (Ru‐HT) in the dehydrogenative synthesis of structurally important acridine‐1,8‐dione derivatives. To highlight the practical utility, the gram‐scale synthesis of acridine‐1,8‐dione and the successful recyclability of the catalyst were shown.
Topics & Concepts
AcridineChemistryDehydrogenationHydrotalciteCatalysisCombinatorial chemistryGreen chemistryAcridine derivativesRutheniumOrganic chemistryReaction mechanismStereochemistryAsymmetric Hydrogenation and CatalysisCatalytic Cross-Coupling ReactionsNanomaterials for catalytic reactions